A qualifying E spouse is employment-authorized incident to status, so the spouse's work need not be inside the enterprise. Children in E-2 dependent status may study but cannot work.
Spousal work is independent of the investment
Hypothetical example: This is often decisive for a household weighing a seasonal enterprise, because a spouse's separate income can carry the months when the business earns little. The spouse's authorization arises from status rather than from any role in the invested business, so employment elsewhere is possible. Documentation practices should be confirmed for the specific case, since employers will ask for something they can record.
Dependent children may attend school but do not receive work permission through the parent's status, and a child approaching adulthood should be planned for separately rather than assumed to continue indefinitely. It is also worth separating two different facts that households tend to merge: the spouse's permission to work is an immigration matter, while the spouse's ability to practise a licensed occupation is a state regulatory matter with its own timeline.